Cellular excitability and the regulation of functional neuronal identity: from gene expression to neuromodulation.
نویسندگان
چکیده
David J. Schulz,1 Richard A. Baines,2 Chris M. Hempel,3 Lingjun Li,4 Birgit Liss,5 and Hiroaki Misonou6,7 1Biological Sciences, University of Missouri, Columbia, Missouri 65211, 2Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom, 3Department of Biology and National Center for Behavioral Genomics, Brandeis University, Waltham, Massachusetts 02454, 4School of Pharmacy, Department of Chemistry, and Neuroscience Training Program, University of Wisconsin, Madison, Wisconsin 53705, 5Molecular Neurobiology, Department of Physiology, Marburg University, D-35037 Marburg, Germany, 6Department of Pharmacology, School of Medicine, University of California, Davis, Davis, California 95616, and 7Department of Biomedical Sciences, Dental School, University of Maryland Baltimore, Baltimore, Maryland 21201
منابع مشابه
Electrophysiological investigation of the cellular effect of anethole, the chief constitute of anise, on F1 neuronal excitability in garden snail
Introduction: Anethole is the main constituent of Pimpinella anisum L. (anise), a herbaceous annual plant which has several therapeutic effects. In the folk medicine, anise is employed as an antiepileptic drug. Specifically, this study was focused on the cellular effect of anethole, an aromatic compound in essential oils from anise and camphor. Anethole has various physiological effects on t...
متن کاملPotential roles of 5´ UTR and 3´ UTR regions in post-trans-criptional regulation of mouse Oct4 gene in BMSC and P19 cells
Objective(s):OCT4 is a transcription factor required for pluripotency during early embryogenesis and the maintenance of identity of embryonic stem cells and pluripotent cells. Therefore, the effective expression regulation of this gene is highly critical. UTR regions are of great significance to gene regulation. In this study, we aimed to investigate the potential regulatory role played by 5´UT...
متن کاملCloning and Sequence Analysis of Gene Encoding OipA from Iranian Clinical Helicobacter pylori
Background: Outer inflammatory protein A (OipA) is one of the important adhesins of H. pylori and a valuable candidate for vaccine development. Its gene is under "on-off" switch status which correlates with OipA protein expression. Objectives: We aimed to obtain a recombinant OipA clone (with "on" status) from an Iranian clinical isolate. Materials and Methods: A clinical H. pylori-isolate demo...
متن کاملPrenatal stress increased γ2 GABAA receptor subunit gene expression in hippocampus and potentiated pentylenetetrazol-induced seizure in rats
Objective(s): Stress during pregnancy is able to bring extensive effects on neurobehavioral development in offspring. The GABAergic system plays a pivotal role in neuronal excitability, which can be affected by prenatal stress (PS). This study aimed to evaluate impact of the PS on γ2 subunit of gamma-aminobutyric acid A (GABAA) receptor gene expression in the hippocamp...
متن کاملFunctional Analysis of a Pomegranate (Punica granatum L.) MYB Transcription Factor Involved in the Regulation of Anthocyanin Biosynthesis
Background: Pomegranate fruit (Punica granatum L.) is a rich source of anthocyanin pigments resulting in vibrant colours and anti-oxidant contents. Although the intensity and pattern of anthocyanin biosynthesis in fruit are strongly influenced by R2R3-MYB transcription factors, little is known about the regulation and role of MYB in anthocyanin pathway of pomegranate. Objectives: The present st...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of neuroscience : the official journal of the Society for Neuroscience
دوره 26 41 شماره
صفحات -
تاریخ انتشار 2006